Antofagasta ANT v |  Deportes Limache LIM | P.A. | |
| 1st Leg |
Audax Italiano AUD v |  San Antonio Unido SAN | P.A. | |
| 1st Leg |
Cobresal COB v |  Barnechea BAR | P.A. | |
| 1st Leg |
Colo Colo COL v |  Deportes Temuco DEP | P.A. | |
| 1st Leg |
Coquimbo Unido COQ v |  Melipilla MEL | P.A. | |
| 1st Leg |
Curicó Unido UNI v |  Santiago Wanderers STW | P.A. | |
| 1st Leg |
General Velásquez GVE v |  Universidad de Chile U. de Chile | P.A. | |
| 1st Leg |
Huachipato HUA v |  Puerto Montt PMO | P.A. | |
| 1st Leg |
La Serena LSE v |  Universidad de Concepción UdeC | P.A. | |
| 1st Leg |
Magallanes MAG v |  Everton CD EVE | P.A. | |
| 1st Leg |
Ñublense ÑUB v |  Independiente de Cauquenes CAU | P.A. | |
| 1st Leg |
O'Higgins OHI v |  Fernández Vial FVI | P.A. | |
| 1st Leg |
Palestino PALE v |  Cobreloa COB | P.A. | |
| 1st Leg |
Unión Española UNI v | Provincial Ovalle OVA | P.A. | |
| 1st Leg |
Unión La Calera ULC v |  Santiago Morning SMO | P.A. | |
| 1st Leg |
Universidad Católica CDUC v |  Unión San Felipe USF | P.A. | |
| 1st Leg |
